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Immunoprofiling Identifies Functional B and T Cell Subsets Induced by an Attenuated Whole Parasite Malaria Vaccine as Correlates of Sterile Immunity

Immune correlates of protection remain elusive for most vaccines. An identified immune correlate would accelerate the down-selection of vaccine formulations by reducing the need for human pathogen challenge studies that are currently required to determine vaccine efficacy. Immunization via mosquito-...

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Detalles Bibliográficos
Autores principales: Mura, Marie, Lu, Pinyi, Atre, Tanmaya, Bolton, Jessica S., Duncan, Elizabeth H., Chaudhury, Sidhartha, Bergmann-Leitner, Elke S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780163/
https://www.ncbi.nlm.nih.gov/pubmed/35062785
http://dx.doi.org/10.3390/vaccines10010124