Pro-inflammatory mediators released by activated monocytes promote aortic valve fibrocalcific activity

BACKGROUND: Calcific aortic valve disease (CAVD) is the most prevalent heart valve disorder in the elderly. Valvular fibrocalcification is a characteristic pathological change. In diseased valves, monocyte accumulation is evident, and aortic valve interstitial cells (AVICs) display greater fibrogeni...

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Detalles Bibliográficos
Autores principales: Zhang, Peijian, The, Erlinda, Luo, Zichao, Zhai, Yufeng, Yao, Qingzhou, Ao, Lihua, Fullerton, David A., Xu, Dingli, Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780233/
https://www.ncbi.nlm.nih.gov/pubmed/35062861
http://dx.doi.org/10.1186/s10020-022-00433-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780233/
https://www.ncbi.nlm.nih.gov/pubmed/35062861
http://dx.doi.org/10.1186/s10020-022-00433-4

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