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Pro-inflammatory mediators released by activated monocytes promote aortic valve fibrocalcific activity

BACKGROUND: Calcific aortic valve disease (CAVD) is the most prevalent heart valve disorder in the elderly. Valvular fibrocalcification is a characteristic pathological change. In diseased valves, monocyte accumulation is evident, and aortic valve interstitial cells (AVICs) display greater fibrogeni...

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Detalles Bibliográficos
Autores principales:	Zhang, Peijian, The, Erlinda, Luo, Zichao, Zhai, Yufeng, Yao, Qingzhou, Ao, Lihua, Fullerton, David A., Xu, Dingli, Meng, Xianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780233/ https://www.ncbi.nlm.nih.gov/pubmed/35062861 http://dx.doi.org/10.1186/s10020-022-00433-4

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