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Dissecting the Mycobacterium bovis BCG Response to Macrophage Infection to Help Prioritize Targets for Anti-Tuberculosis Drug and Vaccine Discovery

New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of Mycobacterium tuberculosis after macrophage phagocytosis is a fundamental step in the complex host–pathogen interactions that lead to granuloma formation and disease. Greater underst...

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Detalles Bibliográficos
Autores principales: Medley, Jamie, Goff, Aaron, Bettencourt, Paulo J. G., Dare, Madelaine, Cole, Liam, Cantillon, Daire, Waddell, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780277/
https://www.ncbi.nlm.nih.gov/pubmed/35062774
http://dx.doi.org/10.3390/vaccines10010113