CpG Oligodeoxynucleotides for Anticancer Monotherapy from Preclinical Stages to Clinical Trials

CpG oligodeoxynucleotides (CpG ODNs), the artificial versions of unmethylated CpG motifs that were originally discovered in bacterial DNA, are demonstrated not only as potent immunoadjuvants but also as anticancer agents by triggering toll-like receptor 9 (TLR9) activation in immune cells. TLR9 acti...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongkun, Kuo, Jimmy Chun-Tien, Yao, Siyu, Zhang, Chi, Khan, Hira, Lee, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780291/
https://www.ncbi.nlm.nih.gov/pubmed/35056969
http://dx.doi.org/10.3390/pharmaceutics14010073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780291/
https://www.ncbi.nlm.nih.gov/pubmed/35056969
http://dx.doi.org/10.3390/pharmaceutics14010073

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