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Heart-specific DNA methylation analysis in plasma for the investigation of myocardial damage

BACKGROUND: Circulating cell-free DNA (cfDNA) can be released when myocardial damage occurs. METHODS: Here, we used the methylated CpG tandem amplification and sequencing (MCTA-seq) method for analyzing dynamic changes in heart-derived DNA in plasma samples from myocardial infarction (MI) patients....

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Detalles Bibliográficos
Autores principales: Ren, Jie, Jiang, Lin, Liu, Xiaomeng, Liao, Yuhan, Zhao, Xueyan, Tang, Fuchou, Yu, Huimin, Shao, Yibing, Wang, Jizheng, Wen, Lu, Song, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780310/
https://www.ncbi.nlm.nih.gov/pubmed/35062960
http://dx.doi.org/10.1186/s12967-022-03234-9