Cargando…

Effect of mRNA Delivery Modality and Formulation on Cutaneous mRNA Distribution and Downstream eGFP Expression

In vitro transcribed messenger ribonucleic acid (mRNA) constitutes an emerging therapeutic class with several clinical applications. This study presents a systematic comparison of different technologies—intradermal injection, microneedle injection, jet injection, and fractional laser ablation—for th...

Descripción completa

Detalles Bibliográficos
Autores principales: Darade, Aditya R., Lapteva, Maria, Hoffmann, Thomas, Mandler, Markus, Schneeberger, Achim, Kalia, Yogeshvar N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780332/
https://www.ncbi.nlm.nih.gov/pubmed/35057047
http://dx.doi.org/10.3390/pharmaceutics14010151