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Effect of mRNA Delivery Modality and Formulation on Cutaneous mRNA Distribution and Downstream eGFP Expression
In vitro transcribed messenger ribonucleic acid (mRNA) constitutes an emerging therapeutic class with several clinical applications. This study presents a systematic comparison of different technologies—intradermal injection, microneedle injection, jet injection, and fractional laser ablation—for th...
Autores principales: | Darade, Aditya R., Lapteva, Maria, Hoffmann, Thomas, Mandler, Markus, Schneeberger, Achim, Kalia, Yogeshvar N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780332/ https://www.ncbi.nlm.nih.gov/pubmed/35057047 http://dx.doi.org/10.3390/pharmaceutics14010151 |
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