Candidates for Repurposing as Anti-Virulence Agents Based on the Structural Profile Analysis of Microbial Collagenase Inhibitors

The pharmacological inhibition of the bacterial collagenases (BC) enzymes is considered a promising strategy to block the virulence of the bacteria without targeting the selection mechanism leading to drug resistance. The chemical structures of the Clostridium perfringens collagenase A (ColA) inhibi...

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Detalles Bibliográficos
Autores principales: Nitulescu, Georgiana, Nitulescu, George Mihai, Zanfirescu, Anca, Mihai, Dragos Paul, Gradinaru, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780423/
https://www.ncbi.nlm.nih.gov/pubmed/35056958
http://dx.doi.org/10.3390/pharmaceutics14010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780423/
https://www.ncbi.nlm.nih.gov/pubmed/35056958
http://dx.doi.org/10.3390/pharmaceutics14010062

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