Quantitative Analysis of the Phase Transition Mechanism Underpinning the Systemic Self-Assembly of a Mechanopharmaceutical Device

Clofazimine (CFZ) is a poorly soluble, weakly basic, small molecule antibiotic clinically used to treat leprosy and is now in clinical trials as a treatment for multidrug resistant tuberculosis and COVID-19. CFZ exhibits complex, context-dependent pharmacokinetics that are characterized by an increa...

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Detalles Bibliográficos
Autores principales: Dunne, Steven, Willmer, Andrew R., Swanson, Rosemary, Almeida, Deepak, Ammerman, Nicole C., Stringer, Kathleen A., Capparelli, Edmund V., Rosania, Gus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780429/
https://www.ncbi.nlm.nih.gov/pubmed/35056910
http://dx.doi.org/10.3390/pharmaceutics14010015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780429/
https://www.ncbi.nlm.nih.gov/pubmed/35056910
http://dx.doi.org/10.3390/pharmaceutics14010015

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