Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma

A root cause for the development and progression of primary open-angle glaucoma might be the loss of the Schlemm’s canal (SC) cell function due to an impaired Angiopoietin-1 (Angpt-1)/Tie2 signaling. Current therapeutic options fail to restore the SC cell function. We propose Angpt-1 mimetic nanopar...

Descripción completa

Detalles Bibliográficos
Autores principales: Mietzner, Raphael, Pawlak, Ramona, Tamm, Ernst R., Goepferich, Achim, Fuchshofer, Rudolf, Breunig, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780450/
https://www.ncbi.nlm.nih.gov/pubmed/35056075
http://dx.doi.org/10.3390/ph15010018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780450/
https://www.ncbi.nlm.nih.gov/pubmed/35056075
http://dx.doi.org/10.3390/ph15010018

Ejemplares similares