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Novel Nanoparticles Based on N,O-Carboxymethyl Chitosan-Dopamine Amide Conjugate for Nose-to-Brain Delivery

A widely investigated approach to bypass the blood brain barrier is represented by the intranasal delivery of therapeutic agents exploiting the olfactory or trigeminal connections nose-brain. As for Parkinson’s disease (PD), characterized by dopaminergic midbrain neurons degeneration, currently ther...

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Detalles Bibliográficos
Autores principales: Trapani, Adriana, Cometa, Stefania, De Giglio, Elvira, Corbo, Filomena, Cassano, Roberta, Di Gioia, Maria Luisa, Trombino, Sonia, Hossain, Md Niamat, Di Gioia, Sante, Trapani, Giuseppe, Conese, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780454/
https://www.ncbi.nlm.nih.gov/pubmed/35057043
http://dx.doi.org/10.3390/pharmaceutics14010147