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Biophysical Characterization of Viral and Lipid-Based Vectors for Vaccines and Therapeutics with Light Scattering and Calorimetric Techniques

Novel vaccine platforms for delivery of nucleic acids based on viral and non-viral vectors, such as recombinant adeno associated viruses (rAAV) and lipid-based nanoparticles (LNPs), hold great promise. However, they pose significant manufacturing and analytical challenges due to their intrinsic stru...

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Detalles Bibliográficos
Autores principales: Markova, Natalia, Cairns, Stefan, Jankevics-Jones, Hanna, Kaszuba, Michael, Caputo, Fanny, Parot, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780473/
https://www.ncbi.nlm.nih.gov/pubmed/35062710
http://dx.doi.org/10.3390/vaccines10010049