Domain 2 of Hepatitis C Virus Protein NS5A Activates Glucokinase and Induces Lipogenesis in Hepatocytes

Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycerides leading to liver steatosis, cirrhosis and hepatocellular carcinoma, w...

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Detalles Bibliográficos
Autores principales: Perrin-Cocon, Laure, Kundlacz, Cindy, Jacquemin, Clémence, Hanoulle, Xavier, Aublin-Gex, Anne, Figl, Marianne, Manteca, Jeremy, André, Patrice, Vidalain, Pierre-Olivier, Lotteau, Vincent, Diaz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780509/
https://www.ncbi.nlm.nih.gov/pubmed/35055105
http://dx.doi.org/10.3390/ijms23020919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780509/
https://www.ncbi.nlm.nih.gov/pubmed/35055105
http://dx.doi.org/10.3390/ijms23020919

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