Sequence Effect on the Activity of DNAzyme with Covalently Attached Hemin and Their Potential Bioanalytical Application

In this work we investigated the effect of a DNA oligonucleotide sequence on the activity of a DNAzyme with covalently attached hemin. For this purpose, we synthesized seven DNA-hemin conjugates. All DNA-hemin conjugates as well as DNA/hemin complexes were characterized using circular dichroism, det...

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Detalles Bibliográficos
Autores principales: Kosman, Joanna, Żukowski, Krzysztof, Csáki, Andrea, Fritzsche, Wolfgang, Juskowiak, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780643/
https://www.ncbi.nlm.nih.gov/pubmed/35062461
http://dx.doi.org/10.3390/s22020500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780643/
https://www.ncbi.nlm.nih.gov/pubmed/35062461
http://dx.doi.org/10.3390/s22020500

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