Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy

Prodrugs are bioreversible medications that should undergo an enzymatic or chemical transformation in the tumor microenvironment to release active drugs, which improve cancer selectivity to reduce toxicities of anticancer drugs. However, such approaches have been challenged by poor therapeutic effic...

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Detalles Bibliográficos
Autores principales: Cho, Hanhee, Shim, Man Kyu, Yang, Suah, Song, Sukyung, Moon, Yujeong, Kim, Jinseong, Byun, Youngro, Ahn, Cheol-Hee, Kim, Kwangmeyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780658/
https://www.ncbi.nlm.nih.gov/pubmed/35056979
http://dx.doi.org/10.3390/pharmaceutics14010083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780658/
https://www.ncbi.nlm.nih.gov/pubmed/35056979
http://dx.doi.org/10.3390/pharmaceutics14010083

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