Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study

Development of drugs that are selectively toxic to cancer cells and safe to normal cells is crucial in cancer treatment. Evaluation of membrane permeability is a key metric for successful drug development. In this study, we have used in silico molecular models of lipid bilayers to explore the effect...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Navaneethan, Kaul, Sunil C., Wadhwa, Renu, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780679/
https://www.ncbi.nlm.nih.gov/pubmed/35054590
http://dx.doi.org/10.3390/membranes12010064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780679/
https://www.ncbi.nlm.nih.gov/pubmed/35054590
http://dx.doi.org/10.3390/membranes12010064

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