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Phosphatidylserine Exposed Lipid Bilayer Models for Understanding Cancer Cell Selectivity of Natural Compounds: A Molecular Dynamics Simulation Study
Development of drugs that are selectively toxic to cancer cells and safe to normal cells is crucial in cancer treatment. Evaluation of membrane permeability is a key metric for successful drug development. In this study, we have used in silico molecular models of lipid bilayers to explore the effect...
Autores principales: | Radhakrishnan, Navaneethan, Kaul, Sunil C., Wadhwa, Renu, Sundar, Durai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780679/ https://www.ncbi.nlm.nih.gov/pubmed/35054590 http://dx.doi.org/10.3390/membranes12010064 |
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