RNA demethylase ALKBH5 in cancer: from mechanisms to therapeutic potential

RNA demethylase ALKBH5 takes part in the modulation of N(6)-methyladenosine (m(6)A) modification and controls various cell processes. ALKBH5-mediated m(6)A demethylation regulates gene expression by affecting multiple events in RNA metabolism, e.g., pre-mRNA processing, mRNA decay and translation. M...

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Detalles Bibliográficos
Autores principales: Qu, Jianwei, Yan, Haimeng, Hou, Yifan, Cao, Wen, Liu, Yang, Zhang, Enfan, He, Jingsong, Cai, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780705/
https://www.ncbi.nlm.nih.gov/pubmed/35063010
http://dx.doi.org/10.1186/s13045-022-01224-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780705/
https://www.ncbi.nlm.nih.gov/pubmed/35063010
http://dx.doi.org/10.1186/s13045-022-01224-4

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