Successful Dendrimer and Liposome-Based Strategies to Solubilize an Antiproliferative Pyrazole Otherwise Not Clinically Applicable

Water-soluble formulations of the pyrazole derivative 3-(4-chlorophenyl)-5-(4-nitrophenylamino)-1H-pyrazole-4-carbonitrile (CR232), which were proven to have in vitro antiproliferative effects on different cancer cell lines, were prepared by two diverse nanotechnological approaches. Importantly, wit...

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Detalles Bibliográficos
Autores principales: Alfei, Silvana, Spallarossa, Andrea, Lusardi, Matteo, Zuccari, Guendalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780786/
https://www.ncbi.nlm.nih.gov/pubmed/35055251
http://dx.doi.org/10.3390/nano12020233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780786/
https://www.ncbi.nlm.nih.gov/pubmed/35055251
http://dx.doi.org/10.3390/nano12020233

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