Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB

Platelets play a critical role in arterial thrombosis. Rutaecarpine (RUT) was purified from Tetradium ruticarpum, a well-known Chinese medicine. This study examined the relative activity of RUT with NF-κB inhibitors in human platelets. BAY11-7082 (an inhibitor of IκB kinase [IKK]), Ro106-9920 (an in...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Chieh, Hou, Shaw-Min, Wu, Ming-Ping, Hsia, Chih-Wei, Jayakumar, Thanasekaran, Hsia, Chih-Hsuan, Bhavan, Periyakali Saravana, Chung, Chi-Li, Sheu, Joen-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780806/
https://www.ncbi.nlm.nih.gov/pubmed/35056795
http://dx.doi.org/10.3390/molecules27020476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780806/
https://www.ncbi.nlm.nih.gov/pubmed/35056795
http://dx.doi.org/10.3390/molecules27020476

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