Efficient Delivery of Hydrophilic Small Molecules to Retinal Cell Lines Using Gel Core-Containing Solid Lipid Nanoparticles

In this study, we developed a novel solid lipid nanoparticle (SLN) formulation for drug delivery of small hydrophilic cargos to the retina. The new formulation, based on a gel core and composite shell, allowed up to two-fold increase in the encapsulation efficiency. The type of hydrophobic polyester...

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Detalles Bibliográficos
Autores principales: Huang, Li, Himawan, Erico, Belhadj, Soumaya, Pérez García, Raúl Oswaldo, Paquet Durand, François, Schipper, Nicolaas, Buzgo, Matej, Simaite, Aiva, Marigo, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780956/
https://www.ncbi.nlm.nih.gov/pubmed/35056970
http://dx.doi.org/10.3390/pharmaceutics14010074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780956/
https://www.ncbi.nlm.nih.gov/pubmed/35056970
http://dx.doi.org/10.3390/pharmaceutics14010074

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