Evaluation of the Pharmacokinetics of the Pancreastatin Inhibitor PSTi8 Peptide in Rats: Integration of In Vitro and In Vivo Findings

PSTi8 is a pancreastatin inhibitory peptide that is effective in the treatment of diabetic models. This study investigates the pharmacokinetic (PK) properties of PSTi8 in Sprague Dawley rats, for the first time. In vitro and in vivo PK studies were performed to evaluate the solubility, stability in...

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Detalles Bibliográficos
Autores principales: Valicherla, Guru R., Katekar, Roshan A., Dadge, Shailesh, Riyazuddin, Mohammed, Syed, Anees A., Singh, Sandeep K., Husain, Athar, Wahajuddin, Muhammad, Gayen, Jiaur R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780964/
https://www.ncbi.nlm.nih.gov/pubmed/35056659
http://dx.doi.org/10.3390/molecules27020339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8780964/
https://www.ncbi.nlm.nih.gov/pubmed/35056659
http://dx.doi.org/10.3390/molecules27020339

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