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Tilorone-Dihydrochloride Protects against Rift Valley Fever Virus Infection and Disease in the Mouse Model

Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and the Middle East that can affect humans and ruminant livestock. Currently, there are no approved vaccines or therapeutics for the treatment of severe RVF disease in humans. Tilorone-dihydrochloride (Tilorone) is a broa...

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Detalles Bibliográficos
Autores principales: Johnson, Kendra N., Kalveram, Birte, Smith, Jennifer K., Zhang, Lihong, Juelich, Terry, Atkins, Colm, Ikegami, Tetsuro, Freiberg, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781158/
https://www.ncbi.nlm.nih.gov/pubmed/35056541
http://dx.doi.org/10.3390/microorganisms10010092