An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles

Glycogen phosphorylase (GP) is a key enzyme in the glycogenolysis pathway. GP inhibitors are currently under investigation as a new liver-targeted approach to managing type 2 diabetes mellitus (DM). The aim of the present study was to evaluate the inhibitory activity of a panel of 52 structurally re...

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Detalles Bibliográficos
Autores principales: Rocha, Sónia, Aniceto, Natália, Guedes, Rita C., Albuquerque, Hélio M. T., Silva, Vera L. M., Silva, Artur M. S., Corvo, Maria Luísa, Fernandes, Eduarda, Freitas, Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781192/
https://www.ncbi.nlm.nih.gov/pubmed/35057487
http://dx.doi.org/10.3390/nu14020306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781192/
https://www.ncbi.nlm.nih.gov/pubmed/35057487
http://dx.doi.org/10.3390/nu14020306

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