The Influence of Fed State Lipolysis Inhibition on the Intraluminal Behaviour and Absorption of Fenofibrate from a Lipid-Based Formulation

The bioavailability of lipophilic drugs may or may not be increased when administered with food due to increased solubilisation in fed state gastrointestinal (GI) fluids. The in vivo interplay between drug solubilisation, lipid phase digestion and drug absorption is complex and remains poorly unders...

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Detalles Bibliográficos
Autores principales: Braeckmans, Marlies, Brouwers, Joachim, Riethorst, Danny, Servais, Cécile, Tack, Jan, Augustijns, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781256/
https://www.ncbi.nlm.nih.gov/pubmed/35057014
http://dx.doi.org/10.3390/pharmaceutics14010119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781256/
https://www.ncbi.nlm.nih.gov/pubmed/35057014
http://dx.doi.org/10.3390/pharmaceutics14010119

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