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Non-Random Pattern of Integration for Epstein-Barr Virus with Preference for Gene-Poor Genomic Chromosomal Regions into the Genome of Burkitt Lymphoma Cell Lines

Background: Epstein-Barr virus (EBV) is an oncogenic virus found in about 95% of endemic Burkitt lymphoma (BL) cases. In latently infected cells, EBV DNA is mostly maintained in episomal form, but it can also be integrated into the host genome, or both forms can coexist in the infected cells. Method...

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Detalles Bibliográficos
Autores principales: Janjetovic, Snjezana, Hinke, Juliane, Balachandran, Saranya, Akyüz, Nuray, Behrmann, Petra, Bokemeyer, Carsten, Dierlamm, Judith, Murga Penas, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781420/
https://www.ncbi.nlm.nih.gov/pubmed/35062290
http://dx.doi.org/10.3390/v14010086