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A potential implication of UDP-glucuronosyltransferase 2B10 in the detoxification of drugs used in pediatric hematopoietic stem cell transplantation setting: an in silico investigation

BACKGROUND: Sinusoidal occlusion syndrome (SOS) is a potentially severe complication following hematopoietic stem cell transplantation (HSCT) in pediatric patients. Treatment related risk factors such as intensity of conditioning, hepatotoxic co-medication and patient related factors such as genetic...

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Detalles Bibliográficos
Autores principales: Robin, Shannon, Hassine, Khalil Ben, Muthukumaran, Jayaraman, Jurkovic Mlakar, Simona, Krajinovic, Maja, Nava, Tiago, Uppugunduri, Chakradhara Rao S., Ansari, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781437/
https://www.ncbi.nlm.nih.gov/pubmed/35062878
http://dx.doi.org/10.1186/s12860-021-00402-5