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A tumor microenvironment-responsive poly(amidoamine) dendrimer nanoplatform for hypoxia-responsive chemo/chemodynamic therapy

BACKGROUND: Chemodynamic therapy is a promising cancer treatment with specific therapeutic effect at tumor sites, as toxic hydroxyl radical (·OH) could only be generated by Fenton or Fenton-like reaction in the tumor microenvironment (TME) with low pH and high level of endogenous hydrogen peroxide....

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Detalles Bibliográficos
Autores principales: Hao, Yingchao, Gao, Yue, Fan, Yu, Zhang, Changchang, Zhan, Mengsi, Cao, Xueyan, Shi, Xiangyang, Guo, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781438/
https://www.ncbi.nlm.nih.gov/pubmed/35062953
http://dx.doi.org/10.1186/s12951-022-01247-6