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Inhalable, Spray-Dried Terbinafine Microparticles for Management of Pulmonary Fungal Infections: Optimization of the Excipient Composition and Selection of an Inhalation Device

Terbinafine is a broad-spectrum antifungal agent with therapeutic potential against pulmonary aspergillosis. The main aim of the current study was to investigate the potential of l-leucine, alone and in combination with mannitol, to improve the performance of spray-dried terbinafine microparticles f...

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Detalles Bibliográficos
Autores principales: Almansour, Khaled, Alfagih, Iman M., Aodah, Alhassan H., Alheibshy, Fawaz, Ali, Raisuddin, Al Hagbani, Turki, Elsayed, Mustafa M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781528/
https://www.ncbi.nlm.nih.gov/pubmed/35056982
http://dx.doi.org/10.3390/pharmaceutics14010087