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Melatonin Attenuates RANKL-Induced Osteoclastogenesis via Inhibition of Atp6v0d2 and DC-STAMP through MAPK and NFATc1 Signaling Pathways

Melatonin is a hormone secreted by the pineal gland that is involved in the biorhythm of reproductive activities. The present study investigated the inhibitory effects of melatonin on osteoclastogenesis in RAW 264.7 cells according to changes in V-ATPase and the corresponding inhibition of the MAPK...

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Detalles Bibliográficos
Autores principales: Kim, Seong-Sik, Jeong, Soon-Pill, Park, Bong-Soo, Kim, In-Ryoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781594/
https://www.ncbi.nlm.nih.gov/pubmed/35056817
http://dx.doi.org/10.3390/molecules27020501