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The Role of Interleukin 18/Interleukin 18-Binding Protein in Adult-Onset Still’s Disease and Systemic Juvenile Idiopathic Arthritis

Interleukin 18 (IL-18) is a pro-inflammatory cytokine of the IL-1 family, whose activity is tightly controlled at the level of production, as well as signalization. Notably, it is buffered by its natural inhibitor, IL-18 binding protein (IL-18BP), which is massively present in circulation in normal...

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Detalles Bibliográficos
Autores principales: Girard-Guyonvarc’h, Charlotte, Harel, Mathilde, Gabay, Cem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781628/
https://www.ncbi.nlm.nih.gov/pubmed/35054124
http://dx.doi.org/10.3390/jcm11020430