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Lipid Membrane State Change by Catalytic Protonation and the Implications for Synaptic Transmission
In cholinergic synapses, the neurotransmitter acetylcholine (ACh) is rapidly hydrolyzed by esterases to choline and acetic acid (AH). It is believed that this reaction serves the purpose of deactivating ACh once it has exerted its effect on a receptor protein (AChR). The protons liberated in this re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781637/ https://www.ncbi.nlm.nih.gov/pubmed/35054529 http://dx.doi.org/10.3390/membranes12010005 |