Reactions of Recombinant Neuronal Nitric Oxide Synthase with Redox Cycling Xenobiotics: A Mechanistic Study

Neuronal nitric oxide synthase (nNOS) catalyzes single-electron reduction of quinones (Q), nitroaromatic compounds (ArNO(2)) and aromatic N-oxides (ArN → O), and is partly responsible for their oxidative stress-type cytotoxicity. In order to expand a limited knowledge on the enzymatic mechanisms of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lesanavičius, Mindaugas, Boucher, Jean-Luc, Čėnas, Narimantas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781745/
https://www.ncbi.nlm.nih.gov/pubmed/35055166
http://dx.doi.org/10.3390/ijms23020980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781745/
https://www.ncbi.nlm.nih.gov/pubmed/35055166
http://dx.doi.org/10.3390/ijms23020980

Ejemplares similares