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Reactions of Recombinant Neuronal Nitric Oxide Synthase with Redox Cycling Xenobiotics: A Mechanistic Study

Neuronal nitric oxide synthase (nNOS) catalyzes single-electron reduction of quinones (Q), nitroaromatic compounds (ArNO(2)) and aromatic N-oxides (ArN → O), and is partly responsible for their oxidative stress-type cytotoxicity. In order to expand a limited knowledge on the enzymatic mechanisms of...

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Detalles Bibliográficos
Autores principales:	Lesanavičius, Mindaugas, Boucher, Jean-Luc, Čėnas, Narimantas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781745/ https://www.ncbi.nlm.nih.gov/pubmed/35055166 http://dx.doi.org/10.3390/ijms23020980

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