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Structural Analysis of Botulinum Neurotoxins Type B and E by Cryo-EM

Botulinum neurotoxins (BoNTs) are the causative agents of a potentially lethal paralytic disease targeting cholinergic nerve terminals. Multiple BoNT serotypes exist, with types A, B and E being the main cause of human botulism. Their extreme toxicity has been exploited for cosmetic and therapeutic...

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Detalles Bibliográficos
Autores principales: Košenina, Sara, Martínez-Carranza, Markel, Davies, Jonathan R., Masuyer, Geoffrey, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781748/
https://www.ncbi.nlm.nih.gov/pubmed/35050991
http://dx.doi.org/10.3390/toxins14010014