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Testing Mitochondrial-Targeted Drugs in iPSC-RPE from Patients with Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. No universally effective treatments exist for atrophic or “dry” AMD, which results from loss of the retinal pigment epithelium (RPE) and photoreceptors and accounts for ≈80% of all AMD patients. Prior studies pr...

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Detalles Bibliográficos
Autores principales: Ebeling, Mara C., Geng, Zhaohui, Stahl, Madilyn R., Kapphahn, Rebecca J., Roehrich, Heidi, Montezuma, Sandra R., Ferrington, Deborah A., Dutton, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781759/
https://www.ncbi.nlm.nih.gov/pubmed/35056119
http://dx.doi.org/10.3390/ph15010062