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Testing Mitochondrial-Targeted Drugs in iPSC-RPE from Patients with Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly. No universally effective treatments exist for atrophic or “dry” AMD, which results from loss of the retinal pigment epithelium (RPE) and photoreceptors and accounts for ≈80% of all AMD patients. Prior studies pr...
Autores principales: | Ebeling, Mara C., Geng, Zhaohui, Stahl, Madilyn R., Kapphahn, Rebecca J., Roehrich, Heidi, Montezuma, Sandra R., Ferrington, Deborah A., Dutton, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781759/ https://www.ncbi.nlm.nih.gov/pubmed/35056119 http://dx.doi.org/10.3390/ph15010062 |
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