Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

The fungal cytochrome P450 lanosterol 14α-demethylase (CYP51) is required for the biosynthesis of fungal-specific ergosterol and is the target of azole antifungal drugs. Despite proven success as a clinical target for azole antifungals, there is an urgent need to develop next-generation antifungals...

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Detalles Bibliográficos
Autores principales: Ruma, Yasmeen N., Keniya, Mikhail V., Tyndall, Joel D. A., Monk, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781857/
https://www.ncbi.nlm.nih.gov/pubmed/35050009
http://dx.doi.org/10.3390/jof8010069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781857/
https://www.ncbi.nlm.nih.gov/pubmed/35050009
http://dx.doi.org/10.3390/jof8010069

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