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Genotyping for HLA Risk Alleles to Prevent Drug Hypersensitivity Reactions: Impact Analysis

Human Leukocyte Antigen (HLA) variants can be a risk factor for developing potentially fatal drug hypersensitivity reactions. Our aim was to estimate the potential impact of genotyping for the HLA risk alleles incorporated in the Dutch Pharmacogenetics Working Group (DPWG) guidelines in The Netherla...

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Detalles Bibliográficos
Autores principales: Manson, Lisanne E. N., van den Hout, Wilbert B., Guchelaar, Henk-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781874/
https://www.ncbi.nlm.nih.gov/pubmed/35056062
http://dx.doi.org/10.3390/ph15010004