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Bisulfite Treatment of CG-Rich Track of Trinucleotide Repeat Expansion Disorder: Make the Sequence Less CG Rich

BACKGROUND: Trinucleotide repeat (TNR) expansion is a kind of mutation with instability in the number of microsatellite repeats. This nature of mutation leads to the different kinds of neurological and neuromuscular disorders; among them, fragile-X syndrome is the main cause of intellectual disabili...

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Detalles Bibliográficos
Autores principales: Joz Abbasalian, Zahra, Khanahmad, Hossein, Tabatabaiefar, Mohammad Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781891/
https://www.ncbi.nlm.nih.gov/pubmed/35127573
http://dx.doi.org/10.4103/abr.abr_144_19