Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma

The receptor tyrosine kinase AXL (RTK-AXL) is implicated in therapy resistance and tumor progression in glioblastoma multiforme (GBM). Here, we investigated therapy-induced receptor modifications and how endogenous RTK-AXL expression and RTK-AXL inhibition contribute to therapy resistance in GBM. GB...

Descripción completa

Detalles Bibliográficos
Autores principales: Scherschinski, Lea, Prem, Markus, Kremenetskaia, Irina, Tinhofer, Ingeborg, Vajkoczy, Peter, Karbe, Anna-Gila, Onken, Julia Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781963/
https://www.ncbi.nlm.nih.gov/pubmed/35055167
http://dx.doi.org/10.3390/ijms23020982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781963/
https://www.ncbi.nlm.nih.gov/pubmed/35055167
http://dx.doi.org/10.3390/ijms23020982

Ejemplares similares