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Regulation of the Receptor Tyrosine Kinase AXL in Response to Therapy and Its Role in Therapy Resistance in Glioblastoma

The receptor tyrosine kinase AXL (RTK-AXL) is implicated in therapy resistance and tumor progression in glioblastoma multiforme (GBM). Here, we investigated therapy-induced receptor modifications and how endogenous RTK-AXL expression and RTK-AXL inhibition contribute to therapy resistance in GBM. GB...

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Detalles Bibliográficos
Autores principales:	Scherschinski, Lea, Prem, Markus, Kremenetskaia, Irina, Tinhofer, Ingeborg, Vajkoczy, Peter, Karbe, Anna-Gila, Onken, Julia Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781963/ https://www.ncbi.nlm.nih.gov/pubmed/35055167 http://dx.doi.org/10.3390/ijms23020982

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