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The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in Drosophila

Statins, HMG Coenzyme A Reductase (HMGCR) inhibitors, are a first-line therapy, used to reduce hypercholesterolemia and the risk for cardiovascular events. While sleep disturbances are recognized as a side-effect of statin treatment, the impact of statins on sleep is under debate. Using Drosophila,...

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Detalles Bibliográficos
Autores principales: Alsehli, Ahmed M., Liao, Sifang, Al-Sabri, Mohamed H., Vasionis, Lukas, Purohit, Archana, Behare, Neha, Clemensson, Laura E., Williams, Michael J., Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781969/
https://www.ncbi.nlm.nih.gov/pubmed/35056136
http://dx.doi.org/10.3390/ph15010079