The distinct RNA-interaction modes of a small ZnF domain underlay TUT4(7) diverse action in miRNA regulation

TUT4 and the closely related TUT7 are non-templated poly(U) polymerases required at different stages of development, and their mis-regulation or mutation has been linked to important cancer pathologies. While TUT4(7) interaction with its pre-miRNA targets has been characterized in detail, the molecu...

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Detalles Bibliográficos
Autores principales: Chaves-Arquero, Belén, Collins, Katherine M., Christodoulou, Evangelos, Nicastro, Giuseppe, Martin, Stephen R., Ramos, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782169/
https://www.ncbi.nlm.nih.gov/pubmed/34719327
http://dx.doi.org/10.1080/15476286.2021.1991169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782169/
https://www.ncbi.nlm.nih.gov/pubmed/34719327
http://dx.doi.org/10.1080/15476286.2021.1991169

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