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The distinct RNA-interaction modes of a small ZnF domain underlay TUT4(7) diverse action in miRNA regulation
TUT4 and the closely related TUT7 are non-templated poly(U) polymerases required at different stages of development, and their mis-regulation or mutation has been linked to important cancer pathologies. While TUT4(7) interaction with its pre-miRNA targets has been characterized in detail, the molecu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782169/ https://www.ncbi.nlm.nih.gov/pubmed/34719327 http://dx.doi.org/10.1080/15476286.2021.1991169 |