Sequence-selective purification of biological RNAs using DNA nanoswitches

Nucleic acid purification is a critical aspect of biomedical research and a multibillion-dollar industry. Here we establish sequence-selective RNA capture, release, and isolation using conformationally responsive DNA nanoswitches. We validate purification of specific RNAs ranging in size from 22 to...

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Detalles Bibliográficos
Autores principales: Zhou, Lifeng, Hayden, Andrew, Chandrasekaran, Arun Richard, Vilcapoma, Javier, Cavaliere, Cassandra, Dey, Paromita, Mao, Song, Sheng, Jia, Dey, Bijan K., Rangan, Prashanth, Halvorsen, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782281/
https://www.ncbi.nlm.nih.gov/pubmed/35072148
http://dx.doi.org/10.1016/j.crmeth.2021.100126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782281/
https://www.ncbi.nlm.nih.gov/pubmed/35072148
http://dx.doi.org/10.1016/j.crmeth.2021.100126

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