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Homologous recombination DNA repair gene RAD51, XRCC2 & XRCC3 polymorphisms and breast cancer risk in South Indian women

BACKGROUND: Homologous recombination repair (HRR) accurately repairs the DNA double-strand breaks (DSBs) and is crucial for genome stability. Genetic polymorphisms in crucial HRR pathway genes might affect genome stability and promote tumorigenesis. Up to our knowledge, the present study is the firs...

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Detalles Bibliográficos
Autores principales: Rajagopal, Taruna, Seshachalam, Arun, Rathnam, Krishna Kumar, Talluri, Srikanth, Venkatabalasubramanian, Sivaramakrishnan, Dunna, Nageswara Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782413/
https://www.ncbi.nlm.nih.gov/pubmed/35061678
http://dx.doi.org/10.1371/journal.pone.0259761