Cargando…

Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors

Access to electron acceptors supports oxidized biomass synthesis and can be limiting for cancer cell proliferation, but how cancer cells overcome this limitation in tumors is incompletely understood. Nontransformed cells in tumors can help cancer cells overcome metabolic limitations, particularly in...

Descripción completa

Detalles Bibliográficos
Autores principales: Datta, Rupsa, Sivanand, Sharanya, Lau, Allison N., Florek, Logan V., Barbeau, Anna M., Wyckoff, Jeffrey, Skala, Melissa C., Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782446/
https://www.ncbi.nlm.nih.gov/pubmed/35061540
http://dx.doi.org/10.1126/sciadv.abg6383