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Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors
Access to electron acceptors supports oxidized biomass synthesis and can be limiting for cancer cell proliferation, but how cancer cells overcome this limitation in tumors is incompletely understood. Nontransformed cells in tumors can help cancer cells overcome metabolic limitations, particularly in...
Autores principales: | Datta, Rupsa, Sivanand, Sharanya, Lau, Allison N., Florek, Logan V., Barbeau, Anna M., Wyckoff, Jeffrey, Skala, Melissa C., Vander Heiden, Matthew G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782446/ https://www.ncbi.nlm.nih.gov/pubmed/35061540 http://dx.doi.org/10.1126/sciadv.abg6383 |
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